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Home - Products - GPCR/G Protein - Antibacterial - (-)-Gallocatechin gallate

(-)-Gallocatechin gallate

CAS No. 4233-96-9

(-)-Gallocatechin gallate( (-)-Gallocatechol gallate | CCRIS 9286 )

Catalog No. M18538 CAS No. 4233-96-9

(-)-Gallocatechin gallate is the polyphenol isolated from tea, with cancer-preventive activities. (-)-Gallocatechin gallate decreases osteoclastogenesis at 20 microM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    (-)-Gallocatechin gallate
  • Note
    Research use only, not for human use.
  • Brief Description
    (-)-Gallocatechin gallate is the polyphenol isolated from tea, with cancer-preventive activities. (-)-Gallocatechin gallate decreases osteoclastogenesis at 20 microM.
  • Description
    (-)-Gallocatechol gallate is an HIV integrase inhibitor found in Camilla sinensis. It displays a wide variety of biological activities, including suppressing amyloid formation by islet amyloid polypeptide, preventing nematode hatching, and inhibiting osteoclast differentiation.
  • In Vitro
    The amount of (-)-Gallocatechin gallate does not differ in leaves of different stages, and the content is relatively low. (?)-gallocatechin gallate in combination with active catechins ((?)-epigallocatechin gallate) has synergistic effects on the induction of apoptosis and inhibition of cell growth for PC-9 cells. (?)-gallocatechin gallate shows inhibitory effect on α-Glucosidase and DPPH, with IC50s of 30.2 μM and 12.2 μg/mL.
  • In Vivo
    ——
  • Synonyms
    (-)-Gallocatechol gallate | CCRIS 9286
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    4233-96-9
  • Formula Weight
    458.38
  • Molecular Formula
    C22H18O11
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 150 mg/mL; 327.25 mM
  • SMILES
    C1[C@H]([C@@H](Oc2cc(cc(c12)O)O)c1cc(c(c(c1)O)O)O)OC(=O)c1cc(c(c(c1)O)O)O
  • Chemical Name
    (2S,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl 3,4,5-trihydroxybenzoate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ko CH,et al. Effects of tea catechins, epigallocatechin, gallocatechin, and gallocatechin gallate, on bone metabolism. J Agric Food Chem. 2009 Aug 26;57(16):7293-7.
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